Ubigene Biosciences: Ubigene developed a CRISPR Gene-Editing strategy designer

Ubigene developed a CRISPR Gene-Editing strategy designer - Red Cotton™ . Red Cotton™ is based on our actual successfully gene-editing cases for more than 3000 genes, and the related parameters for more than 800 cell lines, combining with the technical advantages of Ubigene-developed CRISPR-U™ for gene KO. Red Cotton™ includes various one-stop tools covering from strategy design to KO validation, and functions such as gRNA design, primer design, vector design, sequence alignment, etc. Ubigene has comprehensively constructed a powerful gene KO system. No matter you are expert or freshly started researchers, Red Cotton™ can make your gene-KO experiment easier!

Red Cotton™ CRISPR Gene Editing Designer

3 ready-to-use KO cell line strategies | 3000 successful cases of gene KO | Parameters of more than 800 cell line

Red Cotton™ CRISPR gene editing system (Red Cotton™ system), developed by Ubigene, is an automatic system with thousands of gene-editing data, bioinformatics and IT technology. You only need to input your target gene and cell line information, and you will get the following information in a minute: 3sets of ready-to-use KO cell line strategies; More than 800 cell line related parameters; 3000 successful cases of gene knockout.

Tools for gene editing

Red Cotton™ includes various one-stop gene-editing tools, covering from strategy design to KO validation, and functions such as gRNA design, primer design, analysis of sequencing results, etc.

CRISPR-U™

Exclusive innovation, 10 times more efficient in gene-editing.

CRISPR-U™ (based on CRISPR/Cas9 technology), developed by Ubigene, is more efficient than general CRISPR/Cas9 in double-strand breaking, and CRISPR-U™ can greatly improve the efficiency of homologous recombination, easily achieve knockout (KO), point mutation (PM) and knockin (KI) in vitro and in vivo. With CRISPR-U™, Ubigene has successfully modified genes on more than 100 cell lines.

CRISPR/Cas9 recognizes the target sequence with gRNA, and guides Cas9 endonuclease to cut the upstream of PAM, resulting in the double-strand break (DSB) of DNA the target site. To repair the DSB, the cell uses its own DNA repair mechanism to add or delete or replace pieces of DNA sequences via Homology Directed Repair (HDR) or Non-Homologous End Joining (NHEJ).

Red Cotton™ gRNA plasmid bank

Sign-up Red Cotton™ now and over 600 types of gene plasmids are ready for you!

Ubigene has set-up our gRNA plasmid bank, 10000 in-stock plasmids available. Only $80, 3-5 business days!

Ubigene Biosciences

Make genome editing easier

Ubigene Biosciences is co-founded by biological academics and elites from China, the United States, and France. We are located in Guangzhou Science City, which serves as a global center for high technology and innovation. Ubigene Biosciences has 2000㎡ office areas and laboratories, involving genome editing, cell biology technology, and zebrafish research. We provide products and services for plasmids, viruses, cells, and zebrafish. We aim to provide customers with better gene-editing tools for cell or animal research.

Make genome editing easier is the goal of Ubigene. We developed CRISPR-U™ (based on CRISPR/Cas9 technology) which is more efficient than general CRISPR/Cas9 in double-strand breaking, and CRISPR-U™ can greatly improve the efficiency of homologous recombination, easily achieve knockout (KO), point mutation (PM) and knockin (KI) in vitro and in vivo. With CRISPR-U™, Ubigene has successfully edit genes on more than 100 cell lines.

Pragmatism, efficiency, integrity are our business principles. We are committed to providing the best services and products to every customer who chooses us.

Genome Editing Platform
Focusing on the Application of CRISPR-U™ and CRISPR-B™ Gene Editing Technology
1. Provides various types of gene-editing vectors for different species.
2. Provides different virus packaging services, including lentiviruses, adenoviruses and adeno-associated viruses.
3. Provides high-quality services for gene knockout, point mutation, knockin cell lines and microbe.

Cell Biology Platform Cell Biology Platform
Focusing on primary cells
1. Provides over 400 types of primary cells.
2. Provides culture strategies and related products for different cell types.
3. Provides cell biology-related services such as cell isolation, extraction and validation.

Cell gene knockout scheme